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RecruitingObesity, MorbidNASH - Nonalcoholic SteatohepatitisChronic Inflammation

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

Eligible age

30–70 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.

Sponsor: Mayo Clinic

You may qualify if…

  • Undergoing gastric bypass surgery
  • Confirmed AUROC F=0 or F\>2 liver fibrosis
  • Age 30-70 years
  • BMI greater than 40 kg/m2
  • Negative pregnancy test (female only)
  • Lab Values: Normal TSH

You may not qualify if…

  • Autoimmune diseases
  • Hepatitis B or C positive
  • Heavy alcohol use
  • Active smoking history
  • Active cancer history
  • History of asthma
  • History of COPD
  • Taking Plavix or Coumadin

Where it's recruiting

Arizona

Scottsdale

Source: ClinicalTrials.gov · NCT04232566 · last updated 2026-01-28