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RecruitingPlasma Cell Myeloma

Loratadine for the Reduction of G-CSF Induced Bone Pain in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This early phase I trial studies how well loratadine works in reducing granulocyte-colony stimulating factor (G-CSF) induced bone pain in patients with multiple myeloma who are undergoing stem cell mobilization. Loratadine is an antihistamine that may help to reduce or control bone pain during the process of stem cell collection in patients with multiple myeloma.

Sponsor: Rutgers, The State University of New Jersey

You may qualify if…

  • Patient must be able to provide informed consent
  • Patients with confirmed diagnosis of multiple myeloma
  • Able to swallow and retain oral medication
  • All ethnic groups are eligible

You may not qualify if…

  • Non-English speaking person
  • Patients undergoing haploidentical allogeneic hematopoietic stem cell transplant
  • Known allergies, hypersensitivity, or intolerance to any of the study medications, excipients, or similar compounds
  • Any medical complications or conditions that would, in the investigator's judgement, interfere with full participation in the study
  • On therapeutic dose of aspirin (doses greater than 81 mg) within 7 days prior to the start of the study

Where it's recruiting

New Jersey

New Brunswick

Source: ClinicalTrials.gov · NCT04211259 · last updated 2026-05-29

Loratadine for the Reduction of G-CSF Induced Bone Pain in Patients Wi · TrialPath