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RecruitingCerebral Aneurysm

Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The objective of this study is to explore the effects of Sirolimus on the underlying molecular alterations of cerebral aneurysms.

Sponsor: University of Miami

You may qualify if…

  • 1. Undergoing one of the following procedures at Jackson Memorial Hospital:
  • Clipping of an unruptured cerebral artery aneurysm
  • Endovascular treatment of unruptured cerebral aneurysms (including those receiving coiling)
  • 2. ≥ 18 years of age
  • 3. Willing and able to give informed consent

You may not qualify if…

  • 1\) Subjects meeting any of the following criteria will be excluded:
  • Dissecting, traumatic, or mycotic brain aneurysm.
  • Women who are pregnant, or have a positive urine or blood (β-hCG) pregnancy test.
  • Women who are breastfeeding.
  • Any clinically significant psychiatric or psychological disease, which would preclude the patient from completing the protocol.
  • Patients with known Human Immunodeficiency Virus (HIV) infection or other known immunodeficiency.
  • Patient with renal or liver failure
  • Interstitial pneumonitis

Where it's recruiting

Florida

Miami

Source: ClinicalTrials.gov · NCT04141020 · last updated 2026-03-23

Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms · TrialPath