RecruitingMild Traumatic Brain InjuryModerate Traumatic Brain InjuryMild Cognitive Impairment
Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)
Eligible age
30–90 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
This is a research study that aims to examine whether Veterans with mild Traumatic Brain Injuries are at risk for dementia by studying their memory, brain wave activity, brain structure and proteins that can be elevated after brain injury and in dementia.
Sponsor: VA Office of Research and Development
You may qualify if…
- ✓ All Subjects:
- ✓ Intact color vision
- ✓ Visual acuity of 20/30 (or better)
- ✓ Patients must pass effort measures on the TOMM
- ✓ Patients must have intact decision-making capacity
- ✓ Patients must have no contraindications to lumbar puncture including:
- ✓ Being on a blood thinner
- ✓ Aspirin or Plavix
You may not qualify if…
- ✕ All Subjects:
- ✕ If the primary language is not English
- ✕ Are unable to understand the informed consent process
- ✕ Have a clinically significant problem with any of the following conditions:
- ✕ A history of TBI within 1 year of study
- ✕ Suicidal or homicidal ideation requiring intervention
- ✕ Schizophrenia
- ✕ Bipolar disorder
Where it's recruiting
Massachusetts
Boston
Source: ClinicalTrials.gov · NCT04124029 · last updated 2025-09-26