Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma
Eligible age
18–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Intrahepatic cholangiocarcinoma (ICC) is one of the common malignant tumors. Lymph node metastasis is an important factor affecting the poor prognosis of intrahepatic cholangiocarcinoma. The eighth edition of the AJCC guidelines recommends at least 6 lymph nodes to be used for staging. The American Hepatobiliary and Pancreatic Association also recommends the removal of hilar lymph nodes as part of the radical surgery for intrahepatic cholangiocarcinoma. However, some scholars have found that patients with regional lymph nodes have similar survival rates. This contradictory result has prompted more scholars to conduct clinical research to explore the necessity and standardization of lymph node dissection in intrahepatic cholangiocarcinoma.
Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine
You may qualify if…
- ✓ Patients \>18 years of age and ≤80 years of age;
- ✓ Preoperative imaging and laboratory examination for intrahepatic cholangiocarcinoma, intraoperative frozen and postoperative pathology confirmed as intrahepatic cholangiocarcinoma; preoperative imaging assessment is resectable;
- ✓ No obvious lymph node metastasis in preoperative imaging; or negative intraoperative lymph node biopsy
- ✓ Liver function Child-Turcotte-Pugh score A-B grade;
- ✓ Residual liver volume \>30%; can tolerate radical hepatectomy
- ✓ The patient has autonomy, understands and voluntarily signs the written informed consent and is able to complete the follow-up plan;
- ✓ Sign the written informed consent form prior to the test screening.
You may not qualify if…
- ✕ The patient has obvious heart, lung, brain and kidney dysfunction that affects the treatment of intrahepatic cholangiocarcinoma;
- ✕ The patient has a history of other malignant tumors;
- ✕ Liver function Child-Turcotte-Pugh score C;
- ✕ The investigator determined that it was not suitable for the study.
Where it's recruiting
Baltimore
Source: ClinicalTrials.gov · NCT04078230 · last updated 2022-11-09