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RecruitingGliomaGlioblastomaMetastatic Malignant Neoplasm in the Brain

Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intraoperative microdialysis during neurosurgery for central nervous system malignancies. A biomarker is a measurable indicator of the severity or presence of disease state. Information collected in this study may help doctors to develop new strategies to better diagnose, monitor, and treat brain tumors.

Sponsor: Mayo Clinic

You may qualify if…

  • Age \>= 18 years
  • Diagnosis of the following, based on clinical and radiographic evidence:
  • Any glioma
  • Metastatic brain tumor of any primary origin
  • Epileptic focus requiring surgical resection
  • Planned neurosurgical procedure for purposes of biopsy or resection of suspected or previously diagnosed brain tumor (primary or metastatic) or epileptic focus as part of routine clinical care
  • Willing to undergo neurosurgical resection or biopsy at Mayo Clinic (Rochester, Minnesota \[MN\])
  • Ability to understand and the willingness to sign a written informed consent document

You may not qualify if…

  • Vulnerable populations: pregnant women, prisoners or the mentally handicapped
  • Patients who are not appropriate candidates for surgery due to current or past medical history or uncontrolled concurrent illness

Where it's recruiting

Minnesota

Rochester

Source: ClinicalTrials.gov · NCT04047264 · last updated 2026-02-12