RecruitingMenopauseObesity, AbdominalAging
Bioenergetic Effects of Aging and Menopause (BEAM)
Eligible age
40–65 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The menopause transition is associated with increased risk for weight gain and a shift toward storing fat in the belly region, which may increase risk for cardiovascular disease and diabetes. The study will determine whether the stress hormone cortisol contributes to this shift.
Sponsor: University of Colorado, Denver
You may qualify if…
- ✓ Volunteers will be healthy peri/postmenopausal women who are willing and able to undergo the proposed hormone manipulation and study procedures. Women will be at least 6 months but not more than 7 years past the last menstrual period (i.e., late perimenopausal or early postmenopausal) with FSH \>30 IU/L. We will make a major effort to ensure that the women enrolled in this study come from all races and ethnicities and a wide range of socioeconomic and educational levels. Women will be excluded for the reasons listed below.
You may not qualify if…
- ✕ abnormal vaginal bleeding
- ✕ on hormonal contraceptive or menopausal therapy or intention to start during the period of study
- ✕ positive pregnancy test or intention to become pregnant during the period of study
- ✕ lactation
- ✕ known hypersensitivity to degarelix acetate, estradiol, or medroxyprogesterone acetate
- ✕ Center for Epidemiological Studies Depression Scale (CES-D) score \<,16 (unless clinician follow-up and clinical judgement determine they are eligible (will be noted in study chart)
- ✕ current tobacco and/or vape use more than 2 times/week
- ✕ current marijuana or tetrahydrocannabinol (THC) use in any form more than 3 times/week
Where it's recruiting
Colorado
Aurora
Source: ClinicalTrials.gov · NCT04043520 · last updated 2023-12-18