RecruitingCongenital Heart Disease in Children
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
Eligible age
0.3–4.9 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
The proposed study will be a prospective, randomized, double blind, placebo controlled trial to compare the use of a continuous infusion versus intermittent ketorolac on postoperative patients in the pediatric cardiovascular ICU. We intend to determine if the continuous infusion leads to a decreased utilization of opiates when compared to intermittent ketorolac.
Sponsor: Phoenix Children's Hospital
You may qualify if…
- ✓ 1. All patients aged 3 months to 4 years 11months admitted post operatively to the CVICU during the time period in which the study will be ongoing
- ✓ 2. Initiation of study medication within the first 12-24 hours post-operatively
- ✓ 3. The cardiovascular attending of record after review of the intraoperative course and post-operative laboratories determines the patient will receive Ketorolac for pain control
You may not qualify if…
- ✕ 1. Patients that have acute kidney injury, as defined by the letter "I" in the pRIFLE criteria.
- ✕ 2. History of allergy or sensitivity reaction to ketorolac or any NSAID medications.
- ✕ 3. Requiring mechanical circulatory support (ECMO) or continuous renal replacement therapy (CRRT) within the first 48 hours post-operatively
- ✕ 4. Orthotopic heart transplantation
- ✕ 5. Clinically significant bleeding
- ✕ 6. Patients with known pre-operative medical renal disease, renal transplantation history, congenital or acquired renal abnormality or deformity
Where it's recruiting
Arizona
Phoenix
Source: ClinicalTrials.gov · NCT04040452 · last updated 2026-08-12