RecruitingDiabetes Mellitus, Type 2Genetics
Phenotyping Genetic Risk for Type 2 Diabetes
Eligible age
10–70 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2 diabetes.
Sponsor: University of Pennsylvania
You may qualify if…
- ✓ Age 10-70 years
- ✓ Prior participant of the UPenn Biobank or Center for Applied Genomics Biobank and agreed to be recontacted for future research.
- ✓ Adults with BMI 25kg/m2 or higher, children and adolescents with BMI 85th percentile or higher
You may not qualify if…
- ✕ prior diagnosis of type 1, type 2, or secondary diabetes
- ✕ use of medications that would impact glucose and insulin response such as steroids, metformin or other anti-diabetic medication
- ✕ acute illness that may impact insulin and glucose dynamics
- ✕ pregnancy
- ✕ hypothalamic obesity or related genetic disorder of metabolism
- ✕ recent systemic chemotherapy use
- ✕ gastrointestinal impairment or surgery that may impact absorption
- ✕ anemia
Where it's recruiting
Pennsylvania
Philadelphia
Source: ClinicalTrials.gov · NCT04024631 · last updated 2025-09-10