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RecruitingOveractive Bladder SyndromeNeuropathic Bladder

Oxybutynin for Post-surgical Bladder Pain and Urgency

Eligible age

4–8 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

Sponsor: University of California, Davis

You may qualify if…

  • Patients who will undergo bladder surgery that requires an indwelling bladder catheter after surgery.
  • Age Range: Four to 8 years of age are eligible for the study.

You may not qualify if…

  • Patients who have had prior bladder surgery.
  • Patients who have neurologic disease that could impair bladder sensation.
  • Patients who are already taking antimuscarinic or antispasmodic medications.
  • Patients with glaucoma, any neurologic disease, dementia, impaired mentation or disorder of the central nervous system.
  • Patients taking any medication that affects the central nervous system such as antidepressant, anxiolytic or antipsychotic medications.
  • Less than four years of age cannot have the transdermal patch due to fixed dose. Over 8 years of age: less than 5% of our patients, who undergo this surgery, are over 8 years of age and is usually a rare adolescent. Data in an older cohort may confuse the results since they respond differently to bladder surgery due to larger incision and longer hospital stay with a catheter.

Where it's recruiting

California

Sacramento

Source: ClinicalTrials.gov · NCT03952299 · last updated 2026-01-29

Oxybutynin for Post-surgical Bladder Pain and Urgency · TrialPath