RecruitingSleep

Sleep-dependent Learning in Aging

Eligible age

18–80 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate changes in learning following intervals of sleep (overnight and nap) and wake in young and older adults.

Sponsor: University of Massachusetts, Amherst

You may qualify if…

✓ Age 18-80 yrs
✓ Healthy sleeper
✓ No diagnosed sleep or neurodegenerative disorder

You may not qualify if…

✕ 1. Past diagnosis of any sleep disorder or evidence of a sleep disorder as assessed by self-reported sleep quality assessments, a standardized diagnostic interview, and an acclimation night of polysomnography. Using acclimation-night polysomnography, participants will be excluded with an Apnea-Hypopnea Index \>15; a Period-Limb Movement in Sleep index of \>15/hr; sleep-onset latency \> 45 min (indicative of insomnia); or sleep efficiency \< 80% (see Edinger et al., Sleep, 2004). In cases in which questions arise regarding a participants' inclusion or sleep records, a practicing neurologist board-certified in sleep medicine will review the documentation.
✕ 2. Past diagnosis neurological illness or head injury
✕ 3. Reported average sleep per night \< 5 or \> 9 hrs
✕ 4. Current employment involving shift work or an inability to keep a regular sleep schedule during the week prior to testing
✕ 5. Current use of psychotropic, recreational drugs, or sleep-altering medications (sleep medications, cold medicines within the past week, clonidine, sympathomimetic stimulants)
✕ 6. Daily caffeine intake of \> 4 cups (coffee, tea, colas)
✕ 7. Weekly alcohol intake of \> 10 cups
✕ 8. Pregnancy or \< 12 months post-partum

Where it's recruiting

Massachusetts

Amherst

Source: ClinicalTrials.gov · NCT03840083 · last updated 2025-04-03