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RecruitingPre-EclampsiaVascular Diseases

Mechanisms of Pregnancy Vascular Adaptations

Eligible age

18–40 yrs

Accepts

Women

Locations

1 state

Healthy volunteers

Yes

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About this study

The investigators will collect omental tissue (research surgical excision) and placental tissue (standard of care clinical delivery) from both preeclamptic and non-preeclamptic women during their c-section and use these samples to study the blood vessels, specifically the expression/activation of the AT2R.

Sponsor: University of Wisconsin, Madison

You may qualify if…

  • Female
  • Ages 18 to 40 years old
  • Singleton gestation between 28 weeks, 0 days and 41 weeks, 0 days gestational age at the time of consent
  • Undergoing caesarean section, either planned or otherwise with or without trial of labor

You may not qualify if…

  • Treatment of severe hypertension by antihypertensive or use of magnesium sulfate after the patient is hospitalized for the diagnosis of preeclampsia.
  • Any major fetal structural anomalies or aneuploidies
  • Undergoing cesarean section for placental abruption or bleeding complications.
  • Singleton gestation not within 36 weeks, 0 days and 41 weeks, 0 days gestational age at the time of enrollment (delivery)

Where it's recruiting

Wisconsin

Madison

Source: ClinicalTrials.gov · NCT03806283 · last updated 2026-01-20

Mechanisms of Pregnancy Vascular Adaptations · TrialPath