RecruitingALSSCI - Spinal Cord InjuryStroke
ECoG BMI for Motor and Speech Control
Eligible age
21+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
Test the feasibility of using electrocorticography (ECoG) signals to control complex devices for motor and speech control in adults severely affected by neurological disorders.
Sponsor: Karunesh Ganguly
You may qualify if…
- ✓ 1. Age \> 21
- ✓ 2. Limited ability to use upper limbs, based on neurological examination, due to stroke, amyotrophic lateral sclerosis (ALS), multiple sclerosis, cervical spinal cord injury, brainstem stroke, muscular dystrophy, myopathy or severe neuropathy.
- ✓ 3. Disability, defined by a 4 or greater score on the Modified Rankin Scale, must be severe enough to cause loss of independence and inability to perform activities of daily living.
- ✓ 4. If stroke or spinal cord injury, at least 1 year has passed since onset of symptoms
- ✓ 5. Must live within a two-hour drive of UCSF
You may not qualify if…
- ✕ 1. Pregnancy or breastfeeding
- ✕ 2. Inability to understand and/or read English
- ✕ 3. Inability to give consent
- ✕ 4. Dementia, based on history, physical exam, and MMSE
- ✕ 5. Active depression (BDI \> 20) or other psychiatric illness (active general anxiety disorder, schizophrenia, bipolar disorder, obsessive-compulsive disorder (OCD), or personality disorders (e.g. multiple personality disorder, borderline personality disorder, etc.)
- ✕ 6. History of suicide attempt or suicidal ideation
- ✕ 7. History of substance abuse
- ✕ 8. Co-morbidities including ongoing anticoagulation, uncontrolled hypertension, cancer, or major organ system failure
Where it's recruiting
California
San Francisco
Source: ClinicalTrials.gov · NCT03698149 · last updated 2026-05-05