Bariatric Surgery and Pharmacokinetics of Irbesartan
Eligible age
18–70 yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on irbesartan are investigated.
Sponsor: Norwegian University of Science and Technology
You may qualify if…
- ✓ Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
- ✓ Being a Norwegian citizen
You may not qualify if…
- ✕ Having previously undergone resections in the GI-tract
Source: ClinicalTrials.gov · NCT03476603 · last updated 2025-06-06