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RecruitingDCISStage 0 Breast CancerDuctal Breast Carcinoma In Situ

The PREDICT Registry:

Eligible age

30–85 yrs

Accepts

Women

Locations

16 states

Healthy volunteers

No

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About this study

This is a prospective, non-interventional (observational) cohort study conducted within the medical network of the participating investigators and institutions. Patients meeting the eligibility criteria (see below) will be eligible for participation and the investigators will obtain written informed consent. A central Institutional Review Board (IRB), WCG IRB, will approve the protocol and each participating institution.

Sponsor: PreludeDx

You may qualify if…

  • 1. Patient must have histologically confirmed ductal carcinoma in situ (DCIS) in a single breast (presence of lobular carcinoma in situ (LCIS) or other benign breast disease in addition to DCIS is acceptable).
  • 2. Patient must have the DCISionRT test ordered during routine patient care.
  • 3. Patient must be eligible for or have recently completed breast conserving surgery.
  • 4. Patient must be eligible to receive radiation and/or systemic treatment.
  • 5. Patient must be 30 to 85 years old.
  • 6. Patient must have tumor size of less than 6 cm.
  • 7. Patient must have been diagnosed with DCIS within 120 days of consent.

You may not qualify if…

  • 1. Patient tissue is insufficient to generate DCISionRT test results or required DCISionRT inputs (age, tumor size, margin status, palpability) are missing.
  • 2. Patient has evidence of invasive breast cancer, including microinvasion, lymph node involvement, or Paget's disease of the nipple or suspicious mammogram findings in the lymph nodes or contralateral breast.
  • 3. Patient has been surgically treated with an ipsilateral mastectomy for primary DCIS.
  • 4. Patient has had any prior ipsilateral or contralateral breast DCIS or invasive breast cancer.
  • 5. Patient has a prior history of in-field radiation in the ipsilateral breast.
  • 6. Patient has had prior systemic endocrine or chemotherapy prior to testing.
  • 7. Patient is pregnant.

Where it's recruiting

Arizona

Scottsdale

California

La Jolla · San Mateo

Colorado

Aurora

Florida

Jacksonville · Tampa

Georgia

Atlanta

Illinois

Evanston

Maryland

Baltimore

Michigan

Royal Oak · Troy

Missouri

St Louis

New York

Brooklyn · Lake Success · Mineola · New York

Ohio

Akron · Cleveland · Columbus

Source: ClinicalTrials.gov · NCT03448926 · last updated 2026-04-17

The PREDICT Registry: · TrialPath