RecruitingCirrhosis
Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
To determine the rate and mechanisms of skeletal muscle protein synthesis and breakdown in cirrhotic patients by using multiple tracers and single muscle biopsies.
Sponsor: The Cleveland Clinic
You may qualify if…
- ✓ The diagnosis of cirrhosis based on liver biopsy and/or clinical, biochemical, and imaging criteria.
- ✓ Patients with Child Pugh score from A5- to B7
- ✓ Control group: Subject in control group should have serum ALT and AST within normal range.
You may not qualify if…
- ✕ diabetes
- ✕ cancer
- ✕ kidney failure
- ✕ pregnancy
- ✕ recent surgery (bowel resection or Gastric bypass operation)
- ✕ Advanced cardiac or pulmonary disease
- ✕ patient with thyroid disease \& Coagulopathy ( INR \>1.4 and platelet count \<80,000/ml)
Where it's recruiting
Ohio
Cleveland
Source: ClinicalTrials.gov · NCT03225677 · last updated 2026-09-24