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RecruitingSpinal Cord Injury, Acute

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

Eligible age

18–70 yrs

Accepts

All genders

Locations

7 states

Healthy volunteers

No

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About this study

This study is a prospective multi-center trial designed to determine the safety profile and efficacy of modest (33ºC) intravascular hypothermia following acute cervical (C1 to C8) Spinal Cord Injury (SCI).

Sponsor: University of Miami

You may qualify if…

  • 18 - 70 years of age
  • AIS Grade A - C
  • Glasgow Coma Scale ≥14
  • Able to start hypothermia treatment within 24 hours of injury
  • Non-penetrating injury. Patients urgently taken to the operating room for surgical reduction may also be included.

You may not qualify if…

  • Age \> 70 years
  • AIS Grade D
  • Hyperthermia on admission (\>38.5ºC)
  • Severe systemic injury
  • Severe bleeding
  • Pregnancy
  • Coagulopathy
  • Thrombocytopenia

Where it's recruiting

Arizona

Phoenix

Florida

Miami

Georgia

Atlanta

Indiana

Indianapolis

Maryland

Baltimore

Pennsylvania

Philadelphia

Source: ClinicalTrials.gov · NCT02991690 · last updated 2025-11-21

Systemic Hypothermia in Acute Cervical Spinal Cord Injury · TrialPath