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Studies of Neuregulin/ERBB Signaling in Human Heart

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

Sponsor: Douglas B. Sawyer

You may qualify if…

  • Clinical diagnosis of severe coronary artery disease scheduled to undergo coronary artery bypass surgery.

You may not qualify if…

  • less than 18 years of age
  • unwilling or unable to provide informed consent
  • known active myocarditis
  • hypertrophic cardiomyopathy
  • constrictive pericarditis or other significant pericardial disease
  • severe pulmonary hypertension
  • significant renal impairment (Cr \> 2.5 mg/dL)
  • severe ventricular arrhythmias

Where it's recruiting

Maine

Portland

Source: ClinicalTrials.gov · NCT02820233 · last updated 2025-04-03

Studies of Neuregulin/ERBB Signaling in Human Heart · TrialPath