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RecruitingChronic Obstructive Pulmonary Disease

Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study

Eligible age

All ages

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

Chronic obstructive pulmonary disease (COPD) is often caused by cigarette smoking, but genetic predisposition also influences COPD susceptibility. The purpose of this study is to identify genetic factors that predispose some individuals to develop COPD.

Sponsor: Brigham and Women's Hospital

You may qualify if…

  • Early onset of COPD in individuals younger than 53 years old
  • Spirometry results that are indicative of severe COPD (FEV1 \< 40% predicted)
  • Physician-diagnosed COPD

You may not qualify if…

  • Severe alpha-1 antitrypsin deficiency
  • Other chronic lung diseases in participants with COPD (except asthma)
  • Pregnant
  • Any previous lung surgery including lung transplant or lung reduction volume surgery (LVRS); unless prior Pulmonary Function Tests are available

Where it's recruiting

Source: ClinicalTrials.gov · NCT01177618 · last updated 2025-10-24