RecruitingHeart Failure, Congestive
Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.
Sponsor: Johns Hopkins University
You may qualify if…
- ✓ age \> 18 years
- ✓ Healthy subjects: no history of heart disease
- ✓ Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) \<40%
- ✓ Left ventricular hypertrophy: wall thickness \>1.2cm
- ✓ Coronary artery disease: \>50% coronary lesion or positive stress test
You may not qualify if…
- ✕ contraindication to MRI
Where it's recruiting
Maryland
Baltimore
Source: ClinicalTrials.gov · NCT00181259 · last updated 2026-03-09